Professor Mauro Perretti
Mauro is Professor of Immunopharmacology and Dean of Research and Research Impact at Barts and The London School of Medicine and Dentistry, Queen Mary University of London.Mauro began his career in inflammation research by studying the process of leukocyte trafficking with a focus on the bioactions of Annexin A1, under the mentorship of Prof Rod Flower FRS. Determining the impact of endogenous Annexin-A1 on human neutrophil biology (NatMed1996) forged the concept of ‘endogenous anti-inflammatory mediators’ (TiPS1997) prompting the appreciation of resolution mechanisms, or their lack, in human inflammatory pathologies. Over the last two decades he has deciphered several mediators and pathways of resolution in the context of arthritis, sepsis and reperfusion injury, making an internationally recognised contribution to the resolution of inflammation research area. Currently, his focus is on pro-resolving receptors to understand their physio-pathology and define their pro-resolving signature with the ultimate aim to inform innovative therapeutic approaches for the treatment of chronic diseases. As such he aims to add Resolution Pharmacology to the textbooks of Pharmacology of next decade (TiPS2015, NatRevRheumatol2017).